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KMID : 0360220070480030343
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Journal of the Korean Ophthalmological Society
2007 Volume.48 No. 3 p.343 ~ p.347
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Noninfectious Severe Early Chamber Reaction after Penetrating Keratoplasty
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Lim Su-Jin
Kim Su-Young
Kim Man-Soo
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Abstract
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Purpose: To report 8 cases of Noninfectious early anterior chamber reaction after penetrating keratoplasty (PKP), and to review relevant literature.
Methods: Retrospectively, we reviewed medical records of 8 patients who had undergo PKP from March 2001 to May 2004, associated with early severe chamber reaction.
Results: Preoperative diagnosis are corneal opacity (4 cases), keratoconus (2 cases), corneal ectasia after LASIK (1 case) and graft failure (1 case). Although they didn`t show severe chamber reaction at first day after surgery, the anterior chamber reaction with cornea edema and decreased visual acuity had increased with time. We didn`t give the additional treatment except increasing the number of instillation of topical steroid. The inflammation was improved within a week and the complete resolution was achieved during the follow-up in all cases. In all cases posterior synechia and anterior subcapsular opacity were found.
Conclusions: It seems reasonable to conclude that a single common etiologic factor could not responsible for this syndrome. Non-infectious inflammation developing upon PKP may be caused by a multifactorial process like increased IOP, toxic anterior segment syndrome form surgical trauma or hypersensitivity reaction et al and viscoelastics effect. J Korean Ophthalmol Soc 48(3):343-347, 2007
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KEYWORD
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Chamber reaction, Inflammation, Penetrating keratoplasty
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